When attempting to run an application that uses certain Telerik controls, you may run into the error below: System.InvalidOperationException: '~/Telerik.Web.UI.WebResource.axd' is missing in web.config. RadStyleSheetManager requires a HttpHandler
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Read the complete post at http://brad.kingsleyblog.com/post/Resolving-the-error-7eTelerikWebUIWebResourceaxd.aspx